SAB2900053
Anti-NR4A1 (AB1) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Ngfi-b, gfrp1, nak-1, nak1, nerve growth factor inducible-B protein
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p)
Citations:
5
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... NR4A1(3164)
General description
Nuclear receptor subfamily 4 group A member 1 (NR4A1) is a transcription factor expressed in thymocytes. It is part of an orphan nuclear receptor superfamily. The gene encoding this protein is localized on human chromosome 12.
Immunogen
Synthetic 17 amino acid peptide from internal region of human NUR77. Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Horse (100%); Gorilla, Dog, Bat, Panda (94%); Marmoset, Bovine (88%); Mouse, Rat (82%).
Biochem/physiol Actions
Nuclear receptor subfamily 4 group A member 1 (NR4A1) has a role in cell proliferation. It acts as an activator of mechanistic target of rapamycin (mTOR) signaling and regulates apoptosis. The protein modulates genes related to low oxidative stress and growth promotion. NR4A1 has been shown to be expressed in ovarian tumors.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate-buffered saline containing less than 0.1% sodium azide.
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Nuclear receptor subfamily 4, group A, member 1 inhibits extrinsic apoptosis and reduces caspase-8 activity in H2O2-induced human HUC-F2 fibroblasts.
Shimuzu Y
Redox Report (2015)
Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells.
Ashouri JF and Weiss A
Journal of Immunology, 198(2) (2017)
Differential Copy Number Aberrations in Novel Candidate Genes Associated with Progression from In Situ to Invasive Ductal Carcinoma of the Breast
Shaoxi Liao
Genes Chromosomes Cancer (2012)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB2900053-50UG | 04061831476323 |