Anti-PTK7 antibody produced in rabbit

Protein tyrosine kinase-7 (PTK7) is a transmembrane receptor, that belongs to the receptor protein tyrosine kinase (RTKs) family. It has an extracellular immunoglobulin-like domain, a transmembrane domain and an inert tyrosine kinase-like domain. PTK7 is located on human chromosome 6p21.

PTK7 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human PTK7.

Anti-PTK7 antibody has been used in immunohistochemistry.

Protein tyrosine kinase-7 (PTK7) stimulates cell proliferation and invasion. It plays a vital role embryonic development and disease. PTK7 controls radioresistance with the help of nuclear factor-κ B in esophageal squamous cell carcinoma.

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Supplied in PBS with 0.02% sodium azide.

The action of this antibody can be blocked using blocking peptide SBP3500340.

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