SAB3500390
Anti-ELOVL7 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Elongation of very long chain fatty acids protein 7
产品名称
Anti-ELOVL7 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, mouse
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ELOVL7(79993)
General description
ELOVL (Elongation of very long chain fatty acids) fatty acid elongase 7 is expressed in most tissues except heart and skeletal muscles. In human chromosome, the gene ELOVL7 is localised on 5q12.1.
Immunogen
ELOVL7 antibody was raised against a 15 amino acid peptide near the amino terminus of human ELOVL7.
Biochem/physiol Actions
ELOVL7 catalyses the elongation of long chain fatty acids, preferably saturated long chain fatty acids. Elovl7 exhibited activity towards C16-C20 acyl coenzyme A with maximum affinity towards carbon length of C18. Elovl7 expression is regulated by sterol regulatory element-binding protein 1 (SREBP1) and also by other lipogenic enzymes. The expression levels of Elovl7 is higher in prostate cancer leading to its progression.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3500390.
Physical form
Supplied in PBS with 0.02% sodium azide.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Cockayne syndrome caused by paternally inherited 5Mb deletion of 10q11. 2 and a frameshift mutation of ERCC6
Ghai SJ, et al.
European Journal of Medical Genetics, 54(3), 272-276 (2011)
Yuecheng Xi et al.
Journal of virology, 93(21) (2019-08-09)
Human cytomegalovirus (HCMV) replication requires host metabolism. Infection alters the activity in multiple metabolic pathways, including increasing fatty acid elongation and lipid synthesis. The virus-host interactions regulating the metabolic changes associated with replication are essential for infection. While multiple host
Yuecheng Xi et al.
mBio, 12(3) (2021-05-06)
Stress and virus infection regulate lipid metabolism. Human cytomegalovirus (HCMV) infection induces fatty acid (FA) elongation and increases the abundance of lipids with very-long-chain FA (VLCFA) tails. While reprogramming of metabolism can be stress related, the role of stress in
Tatsuro Naganuma et al.
FEBS letters, 585(20), 3337-3341 (2011-10-01)
Very long-chain fatty acids (VLCFAs) have a variety of physiological functions and are related to numerous disorders. The key step of VLCFA elongation is catalyzed by members of the elongase family, ELOVLs. Mammals have seven ELOVLs (ELOVL1-7), yet none of
Kenji Tamura et al.
Cancer research, 69(20), 8133-8140 (2009-10-15)
A number of epidemiologic studies have indicated a strong association between dietary fat intake and prostate cancer development, suggesting that lipid metabolism plays some important roles in prostate carcinogenesis and its progression. In this study, through our genome-wide gene expression
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