产品名称
抗-ZIP8 兔抗, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC39A8(64116)
Application
兔抗ZIP8抗体可用于免疫细胞化学。
Biochem/physiol Actions
溶质载体家族39成员8(SLC39A8)共转运二价金属阳离子,例如镉,锌,锰和铁。它在细胞摄取镉中起着至关重要的作用。该蛋白是核因子κB(NF-κB)的靶标,并在促炎反应中起作用。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多信息。
General description
溶质载体家族39成员8(SLC39A8),也称为锌和铁相关蛋白8(ZIP8),是一种质膜转运蛋白。它是溶质载体基因超家族的一部分。编码SLC39A8的基因位于人染色体4q24上。
Immunogen
ZIP8抗体通过靶向人ZIP8的羧基末端附近的18个氨基酸多肽获得。
Other Notes
可以使用阻断肽 SBP3500598阻断该抗体的作用。
Physical form
以含有0.02%叠氮化钠的PBS形式提供。
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity.
Zhang R
Human Molecular Genetics (2016)
Advances in the genetics of schizophrenia: toward a network and pathway view for drug discovery: Advances in the genetics of schizophrenia
David A
The New York State Dental Journal (2016)
Autosomal-Recessive Intellectual Disability with Cerebellar Atrophy Syndrome Caused by Mutation of the Manganese and Zinc Transporter Gene SLC39A8.
Boycott KM
American Journal of Human Genetics (2015)
ZIP8 regulates host defense through zinc-mediated inhibition of NF-?B.
Liu MJ
Cell Reports (2013)
Cellular localization and developmental
changes of Zip8, Zip14 and transferrin
receptor 1 in the inner ear of rats
changes of Zip8, Zip14 and transferrin
receptor 1 in the inner ear of rats
Dalian Ding
Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, And Medicine (2014)
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