SAB3701426
Monoclonal Anti-AKT pS473 antibody produced in mouse
clone 17F6.B11, purified immunoglobulin
别名:
Anti-8 hydroxy 2’ deoxyguanosine antibody, Anti-C-AKT, Anti-PKB, Anti-Protein kinase B, Anti-RAC-PK-alpha
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
17F6.B11, monoclonal
Application:
ELISA, IHC, WB
Citations:
1
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
17F6.B11, monoclonal
form
buffered aqueous solution
species reactivity
mouse, monkey, rat, human
technique(s)
ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
isotype
IgG1κ
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... AKT1(207)
Immunogen
Synthetic peptide corresponding to residues surrounding S473 of human AKT1 protein, followed by hybridoma development.
Biochem/physiol Actions
Anti-AKT pS473 Monoclonal Antibody was purified from concentrated tissue culture supernate by Protein A chromatography. This antibody is specific for human and mouse AKT protein phosphorylated at S473. A BLAST analysis was used to suggest cross-reactivity with AKT pS473 from human, mouse, rat and chimpanzee sources based on 100% homology with the immunizing sequence. Cross-reactivity with AKT from other sources has not been determined. Cross-reactivity with AKT2 and AKT3 has not been determined.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01% (w/v) Sodium Azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Sonja Kleeschulte et al.
Naunyn-Schmiedeberg's archives of pharmacology (2024-04-23)
Thrombin inhibition suppresses adiposity, WAT inflammation and metabolic dysfunction in mice. Protease-activated receptor (PAR)1 does not account for thrombin-driven obesity, so we explored the culprit role of PAR4 in this context. Male WT and PAR-4-/- mice received a high fat
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