conjugate
unconjugated
Quality Level
antibody form
culture supernatant
antibody product type
primary antibodies
clone
LGALS3BP-A265, monoclonal
form
aqueous solution
mol wt
antigen predicted mol wt 65.2 kDa
species reactivity
human
technique(s)
western blot: suitable
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... LGALS3BP(3959)
General description
Lectin galactoside-binding soluble 3 binding protein (LGALS3BP), a tumor-secreted antigen, is a large oligomeric and highly glycosylated protein. The LGALS3BP gene is located on human chromosome 17q25.
Immunogen
LGALS3BP purified recombinant protein
Biochem/physiol Actions
Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) also known as Mac-2 binding protein (M2BP) acts as a ligand of the lactose-specific S-type lectin, galectin-3. Mac-2 binding protein (M2BP) participates in cell adhesion and in tumor progression. Serum Mac-2 binding protein glycosylation isomer (M2BPGi) is considered as an important marker to study the criticality of liver disease.
Physical form
Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Lung-Yi Mak et al.
World journal of gastroenterology, 25(11), 1398-1408 (2019-03-29)
Liver cirrhosis is a major risk factor for hepatocellular carcinoma (HCC) development in chronic hepatitis B (CHB). Serum Mac-2 binding protein glycosylation isomer (M2BPGi) is a novel serological marker for fibrosis. The role of M2BPGi in prediction of HCC is
G Calabrese et al.
Cytogenetics and cell genetics, 69(3-4), 223-225 (1995-01-01)
Levels of a 90-kDa tumor associated protein, designated 90K (gene symbol LGALS3BP), have been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). 90K appears to be implicated in immune
Tomonori Sugiura et al.
Nutrition, metabolism, and cardiovascular diseases : NMCD, 29(12), 1337-1344 (2019-10-28)
Mac-2 binding protein (M2BP) plays an important role in cell adhesion. In a recent cross-sectional study we reported that serum M2BP concentrations may reflect silent atherosclerosis. The aim of the present prospective follow-up study was to investigate possible relationships between
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB4100313-200UL | 04061836269586 |