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Activity regulated cytoskeleton associated protein (Arc) is encoded by the gene mapped to human chromosome 8q24.3.

synthetic peptide corresponding to a sequence at the C-terminal region of human Arc, conjugated to KLH. The corresponding sequence is identical in rat and mouse Arc.

Activity regulated cytoskeleton associated protein (Arc) plays a vital role in memory formation. It also facilitates activity-dependent plasticity of dendrites. Mutation in the gene has been associated with the development of idiopathic generalized epilepsy (IGE).

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

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