SAB4200519
Anti-GLUT1 (C-terminal) antibody produced in rabbit
~1.0 mg/mL, affinity isolated antibody
别名:
Anti-SLC2A1, Anti-member 1, Anti-solute carrier family 2 (facilitated glucose transporter)
产品名称
Anti-GLUT1 (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~55-70 kDa
species reactivity
mouse, rat, human
concentration
~1.0 mg/mL
technique(s)
western blot: 0.5-1.0 μg/mL using rat spinal cord extracts (S1 fraction)
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SLC2A1(6513)
mouse ... Slc2a1(20525)
rat ... Slc2a1(24778)
Application
Anti-GLUT1 (C-terminal) antibody produced in rabbit has been used in immunoblotting.
Biochem/physiol Actions
GLUT1 is the main glucose transporter in the blood-brain barrier (BBB), which regulates basal glucose levels. Increased expression of GLUT1 is associated with cell growth and in malignant transformation.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Glucose transporter 1 (GLUT1, SLC2A1) belongs to the family of glucose transporters (GLUTs). It is localized to the membrane and is highly expressed in the brain and spinal cord, with a relative high density in the cerebellum. The vascular form of GLUT1 is mainly localized in endothelial cells of blood vessels.
Immunogen
peptide corresponding to a sequence at the C-terminus of human GLUT1, conjugated to KLH. The corresponding sequence is identical in rat and mouse GLUT1.
Physical form
solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Differential localization of glucose transporter isoforms in non-polarized mammalian cells: distribution of GLUT1 but not GLUT3 to detergent-resistant membrane domains
Sakyo T and Kitagawa T
Biochimica et Biophysica Acta - Biomembranes, 1567, 165-175 (2002)
Photobiomodulatory effects of superpulsed 904 nm laser therapy on bioenergetics status in burn wound healing
Yadav A, et al.
Journal of Photochemistry and Photobiology. B, Biology, 162, 77-85 (2016)
Glucose transporters: expression, regulation and cancer
Medina RA and Owen GI
Biological Research, 35(1), 9-26 (2002)
Immunohistochemical localization and quantification of glucose transporters in the mouse brain
Choeiri C, et al.
Neuroscience, 111(1), 19-34 (2002)
Aarón Guerrero et al.
Frontiers in cardiovascular medicine, 8, 644797-644797 (2021-06-29)
Diabetes mellitus (DM) causes high glucose (HG) levels in the plasma and urine. The (pro)renin receptor (PRR) is a key regulator of renal Na+ handling. PRR is expressed in intercalated (IC) cells of the collecting duct (CD) and binds renin
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