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Merck
CN

SAB4200566

Anti-KHSRP antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

别名:

Anti-FBP2, Anti-FUBP2, Anti-KH-type splicing regulatory protein, Anti-KSRP, Anti-MGC99676

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
8
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~82 kDa

species reactivity

rat, mouse, human

concentration

~1.0 mg/mL

technique(s)

immunoprecipitation (IP): 1-2 μg using lysates of human HEK-293T cells, western blot: 0.25-0.50 μg/mL using whole extracts of mouse NIH-3T3 cells

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KHSRP(8570)
mouse ... Khsrp(16549)
rat ... Khsrp(171137)

General description

K-homology type-splicing regulatory protein (KHSRP) is a multifunctional RNA-binding protein. It contains four K homology RNA-binding domains and an unusual C-terminal domain. KHSRP is localized in neural and non-neural cell lines. It is located on the human chromosome at 19p13.3.

Immunogen

synthetic peptide corresponding to an internal region of human KHSRP (GeneID: 8570), conjugated to KLH. The corresponding sequence is identical in rat, mouse, monkey, pig and dog KHSPR.

Application

Anti-KHSRP antibody produced in rabbit may be used in immunoblotting and immunoprecipitation.

Biochem/physiol Actions

Anti-KHSRP recognizes human, mouse and rat KHSRP.
K-homology type-splicing regulatory protein (KHSRP) is involved in several cellular processes such as transcription, mRNA localization and alternative pre-mRNA splicing. It is also involved in mRNA decay and microRNA precursor maturation.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Preparation Note

For continuous use, store at 2-8 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

低风险生物材料
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容


Mapping of theKHSRPGene to a Region of Conserved Synteny on Human Chromosome 19p13. 3 and Mouse Chromosome 17
Ring H Z, et al.
Genomics, 56(3), 350-352 (1999)
A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.
Min H, et al.
Genes & Development, 11(8), 1023-1036 (1997)
Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease
Briata P, et al.
Wiley Interdisciplinary Reviews. RNA, 7(2), 227-240 (2016)



全球贸易项目编号

货号GTIN
SAB4200566-200UL04061837795633