Anti-Digoxin antibody, Mouse monoclonal

Monoclonal Anti-Digoxin (mouse IgG1 isotype) is derived from the hybridoma DI-22 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with digoxin conjugated to keyhole limpet hemocyanin (KLH).

immunized with Digoxin

Monoclonal Anti-Digoxin antibody produced in mouse has been used in:

• enzyme linked immunosorbent assay (ELISA)
• dot blot
• flow cytometry
• immunofluorescence
• DNA hybridization
• in-situ hybridization (ISH)

Digoxin is an uncharged glycoside which is given to humans with congestive heart failure. It enhances the force of myocardial contraction. Anti-digoxin antibodies can be used to reverse the effects of digoxin.

Unlike other oral inotrope, digoxin does not promote mortality. It inhibits sodium potassium ATPase membrane pump.

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