SAB4200673
Monoclonal Anti-α-Amylase 1A antibody produced in mouse
clone AMY-7, purified from hybridoma cell culture
别名:
AMY1, AMY1A, alpha 1A (salivary), amylase
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
AMY-7, monoclonal
Species reactivity:
human, rat, mouse
Application:
IHC
Citations:
4
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
AMY-7, monoclonal
form
buffered aqueous solution
mol wt
~58 kDa
species reactivity
human, rat, mouse
concentration
~1 mg/mL
technique(s)
immunoblotting: 0.25-0.5 μg/mL using rat pancreas tissue extracts., immunohistochemistry: 5-10 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human pancreas sections.
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... AMY1A(276)
mouse ... Amy1(11722)
rat ... Amy1a(24203)
General description
Monoclonal Anti- α-Amylase 1A (mouse IgG1 isotype) is derived from the hybridoma AMY-7 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with an N-terminal His-tagged recombinant human α. α-Amylase 1A, also known as AMY1A belongs to the α-Amylase family. AMY1A is a secreted digestive enzyme produced by the salivary glands and pancreas.
Immunogen
N-terminal His-tagged recombinant human α-Amylase 1A.
Application
Monoclonal Anti-α-Amylase 1A antibody has been used in immunoblotting, immunohistochemistry.
Biochem/physiol Actions
α-Amylase 1A cleaves the glycosidic linkages in starch molecules to produce smaller saccharides such as maltotriose, maltose, and small amounts of glucose. AMY1A has been identified as an indicator in pancreas and salivary gland diseases, as well as lung cancer, ovarian cancer, plasmacytoma and thyroid adenomas.
Physical form
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Subsite mapping of human salivary alpha-amylase and the mutant Y151M
Kandra L, et al.
Febs Letters, 544(1-3), 194-198 (2003)
Paola Serrano Martinez et al.
Oral diseases, 27(1), 52-63 (2020-06-13)
Hyposalivation-related xerostomia is an irreversible, untreatable, and frequent condition after radiotherapy for head and neck cancer. Stem cell therapy is an attractive option of treatment, but demands knowledge of stem cell functioning. Therefore, we aimed to develop a murine parotid
Expression of alpha-amylase isozymes in human thyroid tissues
Doi S, et al.
Cancer research, 51(13), 3544-3549 (1991)
Xian Zhang et al.
Developmental cell, 57(12), 1496-1511 (2022-06-09)
Diabetic patients show elevated plasma IL18 concentrations. IL18 has two receptors: the IL18 receptor (IL18r) and the Na-Cl co-transporter (NCC). Here, we report that IL18 is expressed on islet α cells, NCC on β cells, and IL18r on acinar cells
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