SAB4200680
抗生物素抗体，小鼠单克隆抗体
clone BN-34, purified from hybridoma cell culture
别名:
单克隆抗-生物素 小鼠抗, Bios II, D-生物素, 维生素B7, 维生素H, 辅酶R
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
BN-34, monoclonal
Species reactivity:
canine, human, bovine, rat, mouse
Application:
ELISA, ELISA (i), ICC, IP, WB
Citations:
17
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
BN-34, monoclonal
form
buffered aqueous solution
species reactivity
canine, human, bovine, rat, mouse
concentration
~1 mg/mL
technique(s)
ELISA: suitable, immunocytochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: 0.15-0.3 μg/mL, western blot: suitable
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
生物素是一种重要的双杂环水溶性维生素，是大多数植物和原核生物合成的辅助因子。蛋白质结合生物素通常存在于膳食来源中，如肉类、谷物、蛋黄、肝脏和一些蔬菜。
Immunogen
生物素化KLH
Biochem/physiol Actions
生物素作为乙酰辅酶A、丙酮酸、丙酰辅酶A和3-甲基巴豆酰基-辅酶A羧化酶的辅酶可用于调节糖异生、脂质稳态、多效基因表达以及补充三羧循环的中间体。与组蛋白结合的生物素在染色质重塑、DNA修复和转座子抑制以维持基因组的稳定性中发挥重要作用。生物素水平不足可导致皮炎、结膜炎、脱发和中枢神经系统异常。
Physical form
溶于0.01 M磷酸盐缓冲液（pH 7.4）中，含有15 mM叠氮化钠。
Disclaimer
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Abigail M Wojtowicz et al.
Biomaterials, 31(9), 2574-2582 (2010-01-09)
Healing large bone defects and non-unions remains a significant clinical problem. Current treatments, consisting of auto and allografts, are limited by donor supply and morbidity, insufficient bioactivity and risk of infection. Biotherapeutics, including cells, genes and proteins, represent promising alternative
Hirotaka Takahashi et al.
PloS one, 11(6), e0156718-e0156718 (2016-06-02)
Ubiquitination is a key post-translational modification in the regulation of numerous biological processes in eukaryotes. The primary roles of ubiquitination are thought to be the triggering of protein degradation and the regulation of signal transduction. During protein ubiquitination, substrate specificity
Biotin: a timeless challenge for total synthesis
De Clercq PJ
Chemical Reviews, 97(6), 1755-1792 (1997)
Michael Reinartz et al.
The Journal of biological chemistry, 283(25), 17440-17449 (2008-04-23)
Nitric oxide (NO) is produced by different isoforms of nitric oxide synthases (NOSs) and operates as a mediator of important cell signaling pathways, such as the cGMP signaling cascade. Another mechanism by which NO exerts biological effects is mediated through
Biotin and biotinidase deficiency
Zempleni J, et al.
Expert Review of Endocrinology & Metabolism, 3(6) (2008)
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