SAB4200709
Anti-Collagen Type IV antibody, Mouse monoclonal
clone col-94, purified from hybridoma cell culture
别名:
Anti-col4a1/col4a2
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
col-94, monoclonal
Application:
DB, EM, IHC
Citations:
3
conjugate
unconjugated
Quality Segment
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
col-94, monoclonal
form
buffered aqueous solution
species reactivity
monkey, human
concentration
~1 mg/mL
technique(s)
dot blot: suitable, electron microscopy: suitable, immunohistochemistry: 4-8 μg/mL using formalin-fixed, paraffin-embedded human tongue sections
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... COL4A1(1282)
General description
Anti-Collagen Type IV antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the col-94 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with human collagen Type IV. Collagen Type IV (also known as COL4A) is a key component of the basement membranes (BM), which is found at the basal surface of epithelial and endothelial cells and is essential for tissue strength and polarity. Type IV Collagens are encoded by three pairs of paralogous genes (COL4A1 through COL4A6).
Immunogen
human collagen Type IV
Application
Anti-Collagen Type IV antibody, Mouse monoclonal has been used in immunohistochemistry and dot-blotting.
Biochem/physiol Actions
Collagen Type IV represents a physical barrier against cell invasion. Proteolysis/degradation of Collagen Type IV is essential for cell migration and cancer cells invasion through the ECM into the interstitial tissues.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
闪点 (F)
Not applicable
闪点 (°C)
Not applicable