SAB4300032
抗 磷酸化-STAT1 (pTyr 701 ) 兔抗
affinity isolated antibody
别名:
Anti-DKFZp686B04100 antibody produced in rabbit, Anti-ISGF-3 antibody produced in rabbit, Anti-STAT91 antibody produced in rabbit, Anti-signal transducer and activator of transcription 1, 91kDa antibody produced in rabbit
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p), WB
Citations:
4
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~91 kDa
species reactivity
human, mouse
concentration
1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(T-G-YP-I-K)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr701)
Gene Information
human ... STAT1(6772)
General description
Signal transducer and activator of transcription 1 (STAT1) gene is mapped to human chromosome 2q32.2. It is part of the STAT family of proteins. STAT1 exists in two isoforms, STAT1α and STAT1β with molecular weight of 91kDa and 84kDa, respectively. The protein shows ubiquitous expression.
Immunogen
Peptide sequence around phosphorylation site of tyrosine 701 (T-G-Y(p)-I-K), according to the protein STAT1.
Biochem/physiol Actions
Signal transducer and activator of transcription 1 (STAT1) plays a vital role in interferon (IFN) signaling. Phospho-STAT1 regulates pro- and anti-apoptotic genes following several stress-induced responses. It interacts with p53 and promotes p53-mediated transcriptional gene activity and apoptosis. STAT1 is also an essential factor of stress-induced and DNA damage-induced checkpoint pathways and thus, acts as a tumor suppressor.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable