SAB4300076
Anti-phospho-TP53 (pSer33) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-FLJ92943 antibody produced in rabbit, Anti-LFS1 antibody produced in rabbit, Anti-TRP53 antibody produced in rabbit, Anti-p53 antibody produced in rabbit, Anti-tumor protein p53 antibody produced in rabbit
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About This Item
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
~53 kDa
种属反应性
human
浓度
1 mg/mL
技术
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同位素/亚型
IgG
免疫原序列
(V-L-SP-P-L)
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
phosphorylation (pSer33)
基因信息
human ... TP53(7157)
免疫原
Peptide sequence around phosphorylation site of serine 33 (V-L-S(p)-P-L), according to the protein TP53.
特点和优势
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目标描述
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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