biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~17 kDa
species reactivity
rat, human, mouse
concentration
1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(R-K-SP-T-G)
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer10)
Gene Information
human ... HIST1H3D(8351)
General description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Immunogen
Peptide sequence around phosphorylation site of serine 10 (R-K-S(p)-T-G), according to the protein HIST1H3D.
Features and Benefits
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Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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