Anti-phospho-HDAC4 (pSer⁶³²) antibody produced in rabbit

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Peptide sequence around phosphorylation site of serine 632 (A-Q-S(p)-S-P), according to the protein HDAC4.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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