Anti-OPRM1 (Ab-375) antibody produced in rabbit

Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin.

The gene OPRM1 (opioid receptor μ 1) is mapped to human chromosome 6q24-q25. The gene spans a length of 200kb and contains 11 exons that yield 17 splice variants.

Peptide sequence around aa. 373-377 (H-P-S-T-A), according to the protein OPRM1.

Anti-OPRM1 (Ab-375) antibody produced in rabbit has been used in Western blotting.

The gene OPRM1 (opioid receptor μ 1) encodes a μ opioid receptor that functions in pain perception and addiction to drugs of abuse, such as cocaine, nicotine and alcohol. It serves as a target for opioid drugs, such as morphine, methadone and heroin and opioid peptides (like β - endorphin and endomorphins) and mediates their effects. Single nucleotide polymorphism in the OPRM1 gene is associated with an inclination to drug addiction and lesser response to painful stimuli.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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