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Merck
CN

SAB4301725

Anti-PKD2L1

affinity isolated antibody

别名:

PCL, PKD2L, PKDL, TRPP3

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC
Citations:
2
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunohistochemistry: 1:20-1:100

accession no.

NP_057196

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... PKD2L1(9033)

General description

PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel) is also known as polycystin-L/ transient receptor potential polycystin-3 (TRPP3). It is expressed in brain, kidney, heart, skeletal muscle, spleen, testis, retina and in the bipolar neurons in the tongue taste buds. TRPP3 is present on the surface membrane and/or endoplasmic reticulum membrane of cells. It belongs to the PKD2 gene family. PKD2L1 is mapped to human chromosome 10q25.

Immunogen

Synthetic peptide of human PKD2L1

Biochem/physiol Actions

PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel) participates in hedgehog signaling, intestinal development and sour tasting. It controls ciliary Ca2+ concentration. Mutations in PKD2 results in autosomal dominant kidney disease (ADPKD).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Regulation of TRPP3 channel function by N-terminal domain palmitoylation and phosphorylation.
Zheng W, et al.
The Journal of Biological Chemistry, 291(49), 25678-25691 (2016)
Identification ofPKD2L, a HumanPKD2-Related Gene: Tissue-Specific Expression and Mapping to Chromosome 10q25.
Wu G, et al.
Genomics, 54(3), 564-568 (1998)

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