SAB4500422
Anti-ADORA2A antibody produced in rabbit
affinity isolated antibody
别名:
ADORA2, ADORA2A, Adenosine receptor A2a
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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 44 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ADORA2A(135)
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General description
Anti-ADORA2A Antibody detects endogenous levels of total ADORA2A protein.
Adenosinergic A2A receptor (ADORA2A) is a G-protein-coupled receptor and is expressed in the brain. It is located on human chromosome 22q11.23.
Immunogen
The antiserum was produced against synthesized peptide derived from human ADORA2A.
Immunogen Range: 120-169
Immunogen Range: 120-169
Biochem/physiol Actions
Activation of the adenosine A2a receptor (ADORA2A) prevents T-cell proliferation and production of pro-inflammatory cytokines. Mutations in adenosinergic A2A receptor (ADORA2A) controls the psychomotor vigilance and the effects of caffeine in NREM (non-rapid-eye movement) sleep.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Polymorphisms of ADORA2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioural performance and sleep EEG after sleep deprivation
Bodenmann S, et al.
British Journal of Pharmacology, 165(6), 1904-1913 (2012)
Adenosine A(2A) receptor gene (ADORA2A) variants may increase autistic symptoms and anxiety in autism spectrum disorder.
Freitag CM
European Child & Adolescent Psychiatry, 19(1), 67-74 (2010)
A genetic variation in the ADORA2A gene modifies age at onset in Huntington's disease
Dhaenens CM, et al.
Neurobiology of Disease, 35(3), 474-476 (2009)
[Adenosine A2A receptor as a drug target for treatment of sepsis]
Sivak KV, et al.
Molekuliarnaia Biologiia, 50(2), 231-245 (2016)
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