SAB4500827
Anti-Factor VIII antibody produced in rabbit
affinity isolated antibody
别名:
AHF, F8B, F8C, antihemophilic factor, coagulation factor VIII
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
5
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 267 kDa
species reactivity
mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... F8(2157)
General description
Anti-Factor VIII Antibody detects endogenous levels of total Factor VIII protein.
Blood clotting factor VIII (FVIII), a nonenzymatic cofactor of activated factor IX (FIXa) is of ~330 kDa. It has three homologous A-domains, a unique B-domain and two C-domains. It is located on chromosome Xq28.
Immunogen
The antiserum was produced against synthesized peptide derived from human Factor VIII.
Immunogen Range: 2161-2210
Immunogen Range: 2161-2210
Biochem/physiol Actions
Mutation in the factor VIII gene (F8) results in haemophilia A (HA). Higher levels of VIII:C (FVIII:C) leads to venous and arterial thromboembolism. The factor VIII serve as a procoagulant cofactor in the intrinsic blood coagulation pathway.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable