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Merck
CN

SAB4500930

Anti-MAST3 antibody produced in rabbit

affinity isolated antibody

别名:

KIAA0561, MAST3, Microtubule-associated serine/threonine-protein kinase 3

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
2
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 143 kDa

species reactivity

mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:10000, western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAST3(23031)

General description

Anti-MAST3 Antibody detects endogenous levels of total MAST3 protein. Microtubule associated serine/threonine kinase 3 (MAST3) belongs to the MAST kinase family. It is composed of 1309 amino acids. The MAST3 gene is 53.9kb long and has 27 exons. It is localized on human chromosome 19p13.11. MAST3 possesses four α-helix bundles having various domains, including a protein kinase domain and a PDZ domain.

Immunogen

The antiserum was produced against synthesized peptide derived from human MAST3.

Immunogen Range: 1031-1080

Biochem/physiol Actions

Microtubule associated serine/threonine kinase 3 (MAST3) modulates the activity of nuclear factor κ-B (NF-κB). It may have a role in inflammatory pathways. Knockdown of MAST3 has been shown to reduce NF-κB activity, which is dependent on toll-like receptor-4.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.


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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Genomic alterations identified by array comparative genomic hybridization as prognostic markers in tamoxifen-treated estrogen receptor-positive breast cancer
Wonshik Han
BMC Cancer (2006)
MAST3: a novel IBD risk factor that modulates TLR4 signaling.
Labbe C
Genes and Immunity (2008)



全球贸易项目编号

货号GTIN
SAB4500930-100UG04061835712335