SAB4501277
Anti-GPR35 antibody produced in rabbit
affinity isolated antibody
别名:
GPR35, Probable G-protein coupled receptor 35
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, WB
Citations:
6
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 34 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GPR35(2859)
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General description
Anti-GPR35 Antibody detects endogenous levels of total GPR35 protein.
GPR35 (G protein-coupled receptor 35) is a lysophosphatidic acid receptor. It is highly expressed in the immune and gastrointestinal systems, dorsal root ganglia, cerebellum and brain. It is mapped to human chromosome 2q37.3 .
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR35.
Immunogen Range: 51-100
Immunogen Range: 51-100
Biochem/physiol Actions
GPR35 (G protein-coupled receptor 35) is involved in heart failure and pain perception. It also participates in the formation of gastric cancer. It serves as a receptor for the kynurenine pathway intermediate kynurenic acid. It can also acts as an important lysophosphatidic acid receptor.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Crucial positively charged residues for ligand activation of the GPR35 receptor
Zhao P, et al.
The Journal of Biological Chemistry, 289(6), 3625-3638 (2014)
Cloning of a G-protein-coupled receptor that shows an activity to transform NIH3T3 cells and is expressed in gastric cancer cells
Okumura S, et al.
Cancer Science, 95(2), 131-135 (2004)
Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35
Wang J, et al.
The Journal of Biological Chemistry, 281(31), 22021-22028 (2006)
GPR35 is a novel lysophosphatidic acid receptor
Oka S, et al.
Biochemical and Biophysical Research Communications, 395(2), 232-237 (2010)
GPR35 as a Novel Therapeutic Target
Mackenzie AE, et al.
Frontiers in Endocrinology, 2 (2011)
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