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Merck
CN

SAB4501294

Anti-GLUR1 antibody produced in rabbit

affinity isolated antibody

别名:

GluR-1, GluR-A, GluR-K1, Glutamate receptor 1, Glutamate receptor ionotropic

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunofluorescence
immunohistochemistry
western blot
Species reactivity:
human, mouse, rat
Citations:
4
Technique(s):
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Uniprot accession no.:
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产品名称

Anti-GLUR1 antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 101 kDa

species reactivity

human, mouse, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... GRIA1(2890)

Biochem/physiol Actions

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It has been associated with migraine.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Anti-GLUR1 Antibody detects endogenous levels of total GLUR1 protein.
The gene encoding GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is localized on human chromosome 5q33.2. It is expressed mainly in the brain. GLUR1 is a glutamate receptor subunit, which forms a glutamate-gated ion channel. It is part of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor family.

Immunogen

The antiserum was produced against synthesized peptide derived from human GluR1.

Immunogen Range: 829-878

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Postsynaptic glutamate receptor δ family contributes to presynaptic terminal differentiation and establishment of synaptic transmission
Kuroyanagi T, et al.
Proceedings of the National Academy of Sciences of the USA, 106(12), 4912-4916 (2009)
Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility
Formicola D, et al.
BMC Medical Genetics, 11(1), 103-103 (2010)
Selective disruption of stimulus-reward learning in glutamate receptor gria1 knock-out mice
Mead AN and Stephens DN
The Journal of Neuroscience, 23(3), 1041-1048 (2003)
Functional organization of the GluR1 glutamate receptor promoter
Borges K and Dingledine R
The Journal of Biological Chemistry, 276(28), 25929-25938 (2001)

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