biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 42 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GPR120(338557)
General description
抗-GPR120抗体可检测总GPR120蛋白的内源性水平。
GPR120(G蛋白偶联受体120)也称为游离脂肪酸受体4(FFA4)。它存在于成熟骨细胞中。它定位于人类染色体12q24。
Immunogen
该抗血清是针对衍生自人GPR120的合成肽而生成的。
免疫原范围: 221-270
免疫原范围: 221-270
Biochem/physiol Actions
GPR120(G蛋白偶联受体120)促进骨形成,抑制骨吸收,从而在骨代谢中发挥重要作用。
Features and Benefits
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Physical form
兔IgG,溶于磷酸盐缓冲液(不含Mg2+和Ca2+),pH 7.4,150mM NaCl,0.02%叠氮化钠和50%甘油中。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Chromosome 12q24.31-q24.33 deletion causes multiple dysmorphic features and developmental delay: First mosaic patient and overview of the phenotype related to 12q24qter defects.
Al-Zahrani J, et al.
Molecular Cytogenetics, 4, 9-9 (2011)
Patricia Widmayer et al.
Frontiers in physiology, 6, 53-53 (2015-03-17)
Long-term intake of dietary fat is supposed to be associated with adaptive reactions of the organism and it is assumptive that this is particularly true for fat responsive epithelial cells in the mucosa of the gastrointestinal tract. Recent studies suggest
Yufeng Zhao et al.
Molecular medicine reports, 17(2), 3281-3287 (2017-12-20)
Grifolic acid is a phenolic compound that was first extracted from the mushroom Albatrellus confluens; it acts as an agonist of the free fatty acid receptor (FFAR4). FFAR4 is expressed in macrophages and mediates the anti‑inflammatory effects of n‑3 unsaturated free
Free Fatty Acid Receptor 4 (GPR120) Stimulates Bone Formation and Suppresses Bone Resorption in the Presence of Elevated n-3 Fatty Acid Levels.
Ahn SH, et al.
Endocrinology, 157(7), 2621-2635 (2016)
Seong Hee Ahn et al.
Endocrinology, 157(7), 2621-2635 (2016-05-05)
Free fatty acid receptor 4 (FFA4) has been reported to be a receptor for n-3 fatty acids (FAs). Although n-3 FAs are beneficial for bone health, a role of FFA4 in bone metabolism has been rarely investigated. We noted that
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