SAB4501790
Anti-LY6E antibody produced in rabbit
affinity isolated antibody
别名:
Ly-6E, Lymphocyte antigen 6E, RIG-E, Retinoic acid-induced gene E protein, Thymic shared antigen 1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 13 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000, immunofluorescence: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... LY6E(4061)
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General description
Anti-LY6E Antibody detects endogenous levels of total LY6E protein.
Anti-LY6E Antibody detects endogenous levels of total LY6E protein. LY6E (lymphocyte antigen 6 family member E) is a glycosylphosphatidylinositol-anchored, interferon (IFN)-inducible protein, that is located on human chromosome 8q24. It is also called as RIG-E.
Immunogen
The antiserum was produced against synthesized peptide derived from human LY6E.
Immunogen Range: 17-66
Immunogen Range: 17-66
Biochem/physiol Actions
LY6E (lymphocyte antigen 6 family member E) controls T lymphocytes proliferation, differentiation and development. It induces HIV-1 Infection. Overexpression of LY6E gene in the peripheral blood cells of individuals with SLE (systemic lupus erythematosus) is associated with lupus activity.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.
M Mao, et al.
Proceedings of the National Academy of Sciences of the USA, 93(12), 5910-5914 (1996)
Interferon-inducible LY6E Protein Promotes HIV-1 Infection.
Yu J, et al.
Journal of Biochemistry, 292(11), 4674-4685 (2017)
Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients.
J Tang, et al.
Lupus, 17(9), 805-813 (2008)
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