SAB4501901
Anti-MMP-14 antibody produced in rabbit
affinity isolated antibody
别名:
MATRIX METALLOPROTEINASE 14, MEMBRANE-TYPE, MEMBRANE-TYPE MATRIX METALLOPROTEINASE 1, MT1-MMP, matrix metalloproteinase 14 (membrane-inserted)
产品名称
Anti-MMP-14 antibody produced in rabbit, affinity isolated antibody
technique(s)
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 65 kDa
species reactivity
mouse, rat, human
concentration
~1 mg/mL
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MMP14(4323)
Biochem/physiol Actions
Matrix metalloproteinase-14 (MMP-14) aids in the migration of leukocytes and breaks down collagen. Migration of cells through the extracellular matrix is also mediated by it. MMP-14 has been shown to be associated with tuberculosis and glioma.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-MMP-14 Antibody detects endogenous levels of total MMP-14 protein. Matrix metalloproteinase-14 (MMP-14) is a collagenase localized to the cell membrane. The gene encoding it is present on human chromosome 14.
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP-14.
Immunogen Range: 471-520
Immunogen Range: 471-520
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Marta Smeda et al.
Breast cancer research : BCR, 20(1), 86-86 (2018-08-05)
Mesenchymal transformation of pulmonary endothelial cells contributes to the formation of a metastatic microenvironment, but it is not known whether this precedes or follows early metastasis formation. In the present work, we characterize the development of nitric oxide (NO) deficiency
MT1-MMP silencing by an shRNA-armed glioma-targeted conditionally replicative adenovirus (CRAd) improves its anti-glioma efficacy in vitro and in vivo.
Ulasov I
Cancer Letters (2015)
Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis.
Sathyamoorthy T
Journal of Immunology (2015)
Matrix metalloproteinases in skin.
Kahari VM, Ssaarialho K
Experimental Dermatology (1997)
Ev L Nichols et al.
Current biology : CB, 29(16), 2652-2664 (2019-08-06)
Synaptic vesicles are indispensable for neuronal communication in mature circuits. Synaptic vesicle biogenesis must be concurrent with axon navigation for synaptogenesis, but whether synaptic vesicles are functionally employed in circuit formation before synaptogenesis is poorly understood. Here, we use time-lapse
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