SAB4501927
Anti-MT-ND1 antibody produced in rabbit
affinity isolated antibody
别名:
NADH dehydrogenase subunit 1, NADH-ubiquinone oxidoreductase chain 1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC, WB
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 35 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MT-ND1(4535)
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General description
Anti-MT-ND1 Antibody detects endogenous levels of total MT-ND1 protein.
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) codes for NADH dehydrogenase-1.
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) codes for NADH dehydrogenase-1.
Immunogen
The antiserum was produced against synthesized peptide derived from human MT-ND1.
Immunogen Range: 176-225
Immunogen Range: 176-225
Biochem/physiol Actions
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) plays a vital role in the electron transport chain of oxidative phosphorylation (OXPHOS). Mutations in MT-ND1 gene is observed in individuals with LHON (leber′s hereditary optic neuropathy). Mutation in MT-ND1 results in dextrocardia, ventriculoarterial discordance and tricuspid atresia.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Genetic diversities of MT-ND1 and MT-ND2 genes are associated with high-altitude adaptation in yak.
Shi Y, et al.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis, 29(3), 485-494 (2018)
Determination of a New Mutation in MT?ND 1 Gene of a Patient With Dextrocardia, Ventriculoarterial Discordance, and Tricuspid Atresia.
Hatemi AC, et al.
Artificial Organs, 39(1), 83-84 (2015)
Mitochondrial ND1 variants in 1281 Chinese subjects with Leber's hereditary optic neuropathy.
Ji Y, et al.
Investigative Ophthalmology & Visual Science, 57(6), 2377-2389 (2016)
Engy A Abdel-Rahman et al.
Journal of advanced research, 31, 35-47 (2021-07-02)
Incidents of myocardial infarction and sudden cardiac arrest vary with time of the day, but the mechanism for this effect is not clear. We hypothesized that diurnal changes in the ability of cardiac mitochondria to control calcium homeostasis dictate vulnerability
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