SAB4502012
抗-INOS 兔抗
affinity isolated antibody
别名:
NOS2A, 一氧化氮合成酶, 巨噬细胞, 诱导型
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Species reactivity:
human
Citations:
11
Technique(s):
ELISA: 1:20000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
Uniprot accession no.:
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 131 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NOS2(4843)
Physical form
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
Application
兔抗INOS，C端抗体可用于免疫印迹。
Biochem/physiol Actions
在感染、组织损伤和炎症期间观察到INOS（诱导型一氧化氮合酶）的上调。INOS负责产生NO（一氧化氮），通过诱导血管舒张来控制血流。NO充当神经递质，可以促进免疫反应。NO还可以响应氧化应激、缺氧、炎性细胞因子（TNF-α，IL-1β，IFN-γ）和脂多糖内毒素而产生抗血栓形成和抗炎作用。iNOS比神经元和内皮NOS产生更多的NO。与这两种同工型不同，iNOS与钙无关。INOS可能与2型糖尿病有关。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
General description
INOS（诱导型一氧化氮合酶）基因定位于人类染色体17q11.2。
抗-INOS抗体可检测内源性总INOS蛋白水平。
Immunogen
该抗血清是针对衍生自人iNOS的合成肽而生成的。
免疫原范围： 1101-1150
免疫原范围： 1101-1150
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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