SAB4502043
Anti-OPRD1 antibody produced in rabbit
affinity isolated antibody
别名:
δ-opioid receptor, δ-type opioid receptor, K56, MSL-2, OPRD
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 40 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000, western blot: 1:500-1:1000
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... OPRD(4985)
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General description
Anti-OPRD1 antibody detects endogenous levels of total OPRD1 protein.
The OPRD1 (opioid receptor δ1) gene is mapped to human chromosome 1p35.3 and encodes for a G-protein-coupled receptor. It is abundantly expressed in peripheral tissues.
Immunogen
The antiserum was produced against synthesized peptide derived from human OPRD1.
Immunogen Range: 311-360
Immunogen Range: 311-360
Biochem/physiol Actions
OPRD1 (opioid receptor δ1) is associated with cognitive function and mood driven behavior. Anxiolytic and antidepressant actions are brought about when specific agonists bind to the OPRD1 gene. δ-opioid receptor (DOR) is known to be involved in the progression and development of specific tumours (malignant). Upregulation of this gene is observed in breast cancer, and thus, it can serve as an important therapeutic marker.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Yang-Chao Wei et al.
Oncology reports, 36(5), 2579-2586 (2016-10-26)
δ‑opioid receptor (DOR) belongs to the family of G protein‑coupled receptors (GPCRs). Numerous studies have shown that DOR is widely distributed in human peripheral tissues and is closely related to the development and progression of certain malignant tumours. However, there is controversy in
Louis Gendron et al.
Pharmacological reviews, 68(3), 631-700 (2016-06-28)
Opioids are among the most effective analgesics available and are the first choice in the treatment of acute severe pain. However, partial efficacy, a tendency to produce tolerance, and a host of ill-tolerated side effects make clinically available opioids less
Ann M Manzardo et al.
Gene, 560(2), 184-194 (2015-02-07)
Alcoholism arises from combined effects of multiple biological factors including genetic and non-genetic causes with gene/environmental interaction. Intensive research and advanced genetic technology has generated a long list of genes and biomarkers involved in alcoholism neuropathology. These markers reflect complex
Huihui Ji et al.
PloS one, 12(3), e0172335-e0172335 (2017-03-03)
Aberrant DNA methylation has been observed in the patients with Alzheimer's disease (AD), a common neurodegenerative disorder in the elderly. OPRD1 encodes the delta opioid receptor, a member of the opioid family of G-protein-coupled receptors. In the current study, we
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