SAB4502511
Anti-HECW2 antibody produced in rabbit
affinity isolated antibody
别名:
C2 and WW domain-containing protein 2, E3 ubiquitin-protein ligase HECW2, HECT, NEDD4-like E3 ubiquitin-protein ligase 2
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
2
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 175 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HECW2(57520)
General description
Anti-HECW2 Antibody detects endogenous levels of total HECW2 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human HECW2.
Immunogen Range: 481-530
Immunogen Range: 481-530
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Vidhya Krishnamoorthy et al.
Biochimica et biophysica acta. Molecular cell research, 1865(8), 1088-1104 (2018-05-14)
Lamins constitute the major architectural proteins of the nuclear lamina that help in maintaining nuclear organization. Mutations in lamins are associated with diverse degenerative diseases, collectively termed laminopathies. HECW2, a HECT-type E3 ubiquitin ligase, is transcriptionally upregulated in HeLa cells
Richa Khanna et al.
The FEBS journal, 285(12), 2243-2262 (2018-04-21)
Lamins are key nuclear proteins which are important for maintaining nuclear structure and function. Mutations in lamins cause a spectrum of genetic diseases termed as laminopathies. RING finger containing E3 ubiquitin ligase, RNF123, is transcriptionally upregulated in cells expressing rod
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB4502511-100UG | 04061837190018 |