SAB4502804
Anti-GLUT3, C-Terminal antibody produced in rabbit
affinity isolated antibody
别名:
GLUT-3, GLUT3, Glucose transporter type 3 brain, SLC2A3, Solute carrier family 2 facilitated glucose transporter member 3
产品名称
Anti-GLUT3, C-Terminal antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 53 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC2A3(6515)
Application
Anti-GLUT3, C-Terminal antibody produced in rabbit has been used in immunocytochemistry.
Biochem/physiol Actions
Solute carrier family 2 member 3 (SLC2A3)/ glucose transporter -3 (GLUT-3) along with GLUT1, facilitates the transport of dehydroascorbic acid (DHA). It also plays a vital role in cerebral glucose metabolism, providing energy for the activity of neurons, which, in turn, moderates the excitatory-inhibitory balance impacting both brain development and activity-dependent neural plasticity. SLC2A3 is essential for or optimal preimplantation embryo development and survival. Mutation in the gene increases the risk of susceptibility to attention-deficit/hyperactivity disorder (ADHD).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-GLUT3 Antibody detects endogenous levels of total GLUT3 protein.
Solute carrier family 2 member 3 (SLC2A3), also known as glucose transporter -3 (GLUT-3), is encoded by the gene mapped to human chromosome 12p13.3. The encoded protein belongs to the SLC2 family of GLUTs.
Solute carrier family 2 member 3 (SLC2A3), also known as glucose transporter -3 (GLUT-3), is encoded by the gene mapped to human chromosome 12p13.3. The encoded protein belongs to the SLC2 family of GLUTs.
Immunogen
The antiserum was produced against synthesized peptide derived from human GLUT3.
Immunogen Range: 447-496
Immunogen Range: 447-496
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
The facilitative glucose transporter GLUT3: 20 years of distinction.
Simpson I A, et al.
American Journal of Physiology. Endocrinology and Metabolism, 295(2), E242-E253 (2008)
Energy requirements of odor transduction in the chemosensory cilia of olfactory sensory neurons rely on oxidative phosphorylation and glycolytic processing of extracellular glucose.
Villar P S, et al.
The Journal of Neuroscience, 37(23), 5736-5743 (2017)
Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid.
Rumsey S C, et al.
The Journal of Biological Chemistry, 272(30), 18982-18989 (1997)
slc2a3 single?nucleotide polymorphism and duplication influence cognitive processing and population?specific risk for attention?deficit/hyperactivity disorder.
Merker S, et al.
Journal of Child Psychology and Psychiatry, and Allied Disciplines, 58(7), 798-809 (2017)
The human Hox-bearing chromosome regions did arise by block or chromosome (or even genome) duplications.
Larhammar D, et al.
Genome Research, 12(12), 1910-1920 (2002)
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