SAB4502896
Anti-CD147, C-Terminal antibody produced in rabbit
affinity isolated antibody
别名:
BASI, CD147, basigin, basigin (Ok blood group), collagenase stimulatory factor
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Species reactivity:
mouse, human, rat
Citations:
5
Technique(s):
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Uniprot accession no.:
产品名称
Anti-CD147, C-Terminal antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 42 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BSG(682)
Application
Anti-CD147, C-Terminal antibody has been used in western blotting.
Biochem/physiol Actions
Cluster of differentiation 147 (CD147) is considered as an extracellular matrix metalloproteinase inducer. It participates in several physiological and pathological activities, mainly in tumor invasion and metastasis. CD147 helps in tumor cell-macrophage interactions and stimulates MMPs (matrix metalloproteinases) and vascular endothelial growth factor (VEGF).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-CD147 Antibody detects endogenous levels of total CD147 protein.
Cluster of differentiation 147 (CD147) is a multifunctional trans-membrane glycoprotein and is a member of the immunoglobulin superfamily. It occurs in transmembrane and soluble forms. CD147 is also known as EMMPRIN or basigin (BSG). It is a 57 kDa glycoprotein with two extracellular Ig domains. CD147 is located on human chromosome 19p13.
Cluster of differentiation 147 (CD147) is a multifunctional trans-membrane glycoprotein and is a member of the immunoglobulin superfamily. It occurs in transmembrane and soluble forms. CD147 is also known as EMMPRIN or basigin (BSG). It is a 57 kDa glycoprotein with two extracellular Ig domains. CD147 is located on human chromosome 19p13.
Immunogen
The antiserum was produced against synthesized peptide derived from human CD147.
Immunogen Range: 336-385
Immunogen Range: 336-385
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Simvastatin attenuated rat thoracic aorta remodeling by decreasing ROCK2?mediated CyPA secretion and CD147-ERK1/2-cyclin pathway.
Tang FC, et al.
Molecular Medicine Reports, 16(6), 8123-8129 (2017)
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
Wu B, et al.
Cell Death and Differentiation, 8(7), e2925-e2925 (2017)
CD147 overexpression may serve as a promising diagnostic and prognostic marker for gastric cancer: evidence from original research and literature.
Hu C, et al.
Oncotarget, 8(19), 30888?30899-30888?30899 (2017)
BGMUT: NCBI dbRBC database of allelic variations of genes encoding antigens of blood group systems.
Patnaik SK, et al.
Nucleic Acids Research, 40(D1), D1023-D1029 (2011)
CD147-induced cell proliferation is associated with Smad4 signal inhibition.
Qin H, et al.
Experimental Cell Research, 358(2), 279-289 (2017)
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