Anti-TUSC3 antibody produced in rabbit

Tumor suppressor candidate 3 (TUSC3) codes for a subunit of the endoplasmic reticulum-bound oligosaccharyltransferase complex. It is a 348 amino acid protein, that has 11 exons spanning ∼224 Kbp of the genomic DNA. TUSC3 has five potential transmembrane domains and is located on human chromosome 8p22.

The antiserum was produced against synthesized peptide derived from human TUSC3.

Immunogen Range: 131-180

Anti-TUSC3 antibody has been used in immunohistochemistry, immunoblotting and co-immunoprecipitation.

Tumor suppressor candidate 3 (TUSC3) is a tumor suppressor gene, that is responsible for autosomal recessive mental retardation. It participates in catalyzing the transfer of a 14-sugar oligosaccharide from dolichol to nascent protein. Absence of TUSC3 is associated with lymph node metastasis in larynx and pharynx squamous cell carcinomas.

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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