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Merck
CN

SAB4503258

Anti-Calnexin, C-Terminal antibody produced in rabbit

affinity isolated antibody

别名:

CALX, CANX, IP90, Major histocompatibility complex class I

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UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
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产品名称

Anti-Calnexin, C-Terminal antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 67 kDa

species reactivity

mouse, rat, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... CANX(821)

Biochem/physiol Actions

CANX (calnexin) participates in protein folding and quality control. It is responsible for glycan-independent interaction and retention of mutated Gas3/PMP22 (growth arrest-specific protein 3/peripheral myelin protein 22) proteins involved in Charcot-Marie-Tooth 1A and Dejerine Sottas syndrome.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Anti-Calnexin Antibody detects endogenous levels of total Calnexin protein.

CANX (calnexin) is an endoplasmic reticulum (ER) chaperone. It has a molecular weight of 67kDa. It is a type I transmembrane protein and is located on human chromosome 5q35.

Immunogen

The antiserum was produced against synthesized peptide derived from human Calnexin.

Immunogen Range: 543-592

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
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分析证书(COA)

Lot/Batch Number

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Silvia G Inderbinen et al.
Toxicology letters, 322, 39-49 (2020-01-14)
Exposure to the environmental pollutants organotins is of toxicological concern for the marine ecosystem and sensitive human populations, including pregnant women and their unborn children. Using a placenta cell model, we investigated whether organotins at nanomolar concentrations affect the expression
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Cell biology international, 43(2), 167-173 (2018-12-15)
Cerebral dopamine neurotrophic factor (CDNF) has been considered as potent candidates for the therapy of Parkinson's disease (PD) for which can promote the survival of midbrain dopaminergic neurons. In addition to secret out from cells like other classical neurotrophic factors
Mapping of primary congenital lymphedema to the 5q35.3 region
Evans AL, et al.
American Journal of Human Genetics, 64(2), 547-555 (1999)
Michael Weingartner et al.
PLoS neglected tropical diseases, 16(1), e0009192-e0009192 (2022-01-15)
Echinococcus multilocularis causes alveolar echinococcosis (AE), a rising zoonotic disease in the northern hemisphere. Treatment of this fatal disease is limited to chemotherapy using benzimidazoles and surgical intervention, with frequent disease recurrence in cases without radical surgery. Elucidating the molecular
Hao Liu et al.
Cell biology international, 43(2), 167-173 (2018-12-15)
Cerebral dopamine neurotrophic factor (CDNF) has been considered as potent candidates for the therapy of Parkinson's disease (PD) for which can promote the survival of midbrain dopaminergic neurons. In addition to secret out from cells like other classical neurotrophic factors

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