biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 56 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GPR101(83550)
General description
Anti-GPR101 Antibody detects endogenous levels of total GPR101 protein.
G protein-coupled receptor 101 (GPR101) codes for an an orphan G protein-coupled receptor. It is expressed at high level in the hypothalamus. The GPR101 gene is mapped to human chromosome Xq26.3.
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR101.
Immunogen Range: 451-500
Immunogen Range: 451-500
Biochem/physiol Actions
Mutation in G protein-coupled receptor 101 (GPR101) gene result in acromegaly. The GPR101 protein is expected to play an important role in hypothalamic control of energy homeostasis. Duplication of the GPR101 gene leads to X-linked acrogigantism (XLAG).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study.
Iacovazzo D, et al.
Acta Neuropathologica Communications, 4(1), 56-56 (2016)
Very low frequency of germline GPR101 genetic variation and no biallelic defects with AIP in a large cohort of patients with sporadic pituitary adenomas.
Lecoq AL, et al.
European Journal of Endocrinology, 174(4), 523-530 (2016)
Gigantism: X-linked acrogigantism and GPR101 mutations.
Iacovazzo D and Korbonits M
Growth Hormone & IGF Research, 30-31, 64-69 (2016)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB4503289-100UG | 04061837192128 |