产品名称
抗-磷酸化-CaMK4 (pThr196/200) 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 51 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pThr196/pThr200)
Quality Level
Gene Information
human ... CAMK4(814)
Biochem/physiol Actions
Calcium/calmodulin-dependent kinase 4 (CAMK4) controls blood pressure.This protein plays a major role in the spermatogenesis by phosphorylating protamines.. It controls vascular tone. Absence of CaMK4 gene promotes hypertension.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Calcium/calmodulin-dependent protein kinase IV (CAMK4) is a multifunctional serine/threonine protein kinase. It is present in cells of the nervous and immune systems. This gene is located on human chromosome 5q22.
Immunogen
The antiserum was produced against synthesized peptide derived from human CaMK4 around the phosphorylation site of Thr196/200.
Immunogen Range: 166-215
Immunogen Range: 166-215
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
CAMK4 gene variation is associated with hypertension in a Uygur population
Chen SZ, et al.
Genetics and molecular research : GMR, 15(1) (2016)
Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller
Racioppi L and Means AR
Trends in Immunology, 29(12), 600-607 (2008)
CaMK4 Gene Deletion Induces Hypertension
Santulli G
Journal of the American Heart Association (2012)
Akanksha Roy et al.
International journal of molecular sciences, 25(6) (2024-03-28)
Inherited retinal degenerative diseases (IRDs) are a group of rare diseases that lead to a progressive loss of photoreceptor cells and, ultimately, blindness. The overactivation of cGMP-dependent protein kinase G (PKG), one of the key effectors of cGMP-signaling, was previously
A Khattri et al.
International journal of andrology, 35(6), 810-818 (2012-08-18)
Calcium/calmodulin-dependent protein kinase IV (CAMK4) is a multifunctional serine/threonine protein kinase, which plays an important role in the spermatogenesis by phosphorylating protamines. It has been shown to be involved in the regulation of human sperm motility. Moreover, the Camk4 knockout
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