Anti-phospho-Cortactin (pTyr⁴²¹) antibody produced in rabbit

Cortactin is an actin-related protein 2/3 (Arp2/3) complex–activating and filamentous (F)-actin–binding protein. This protein is coded by CTTN gene that maps to human chromosome 11q13.

The antiserum was produced against synthesized peptide derived from human Cortactin around the phosphorylation site of Tyr421.

Immunogen Range: 388-437

Anti-phospho-Cortactin (pTyr421) antibody has been used in western blotting and immunoprecipitation.

Cortactin controls Arp2/3-mediated actin polymerization. This protein also modulates aggressive cancer cell traits like tumor growth, cancer cell invasion and motility, and serum- and anchorage-independent growth.

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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