SAB4700192
Monoclonal Anti-CD48 antibody produced in mouse
clone MEM-102, purified immunoglobulin, buffered aqueous solution
别名:
Anti-BLAST-1
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MEM-102, monoclonal
Application:
FACS
Citations:
4
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MEM-102, monoclonal
form
buffered aqueous solution
species reactivity
nonhuman primates, human
concentration
1 mg/mL
technique(s)
flow cytometry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CD48(962)
正在寻找类似产品? 访问 产品对比指南
General description
Cluster of differentiation 48 (CD48) molecule, also known as BLAST1, is encoded by the gene mapped to human chromosome 1q23.3. CD48 is a glycosyl-phosphatidyl-inositol (GPI)-anchored cell-surface protein of immunoglobulin superfamily. The encoded protein is expressed on various hematopoietic cells.
The antibody MEM-102 reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
Immunogen
Raji human Burkitt′s lymphoma cell line
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Biochem/physiol Actions
Cluster of differentiation 48 (CD48) acts as an adhesion and co-stimulatory molecule and stimulates various effects in B and T lymphocytes, natural killer cells, mast cells and eosinophils. CD48 interacts with its ligand CD2 and other molecules and promotes rearrangement of signaling factors in lipid rafts, Lck-kinase activity and tyrosine phosphorylation.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Characterization of the Epstein-Barr Virus-Inducible Gene
Encoding the Human Leukocyte Adhesion and
Activation Antigen BLAST-1 (CD48)
Fisher RC and Thorley-Lawson DA
Molecular and Cellular Biology, 11, 1614-1623 (1991)
Soichiro Saito et al.
Oncology reports, 16(5), 949-956 (2006-10-04)
Biliary tract cancers carry dismal prognoses. It is commonly understood that chromosomal aberrations in cancer cells have prognostic and therapeutic implications. However, in biliary tract cancers the genetic changes have not yet been sufficiently studied. The aim of this study
CD48: A co-stimulatory receptor of immunity.
Elishmereni M and Levi-Schaffer F
The International Journal of Biochemistry & Cell Biology, 43, 25-28 (2011)
The genetic differences between gallbladder and bile duct cancer cell lines.
Saito S
Oncology Reports, 16, 949-956 (2006)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持