Monoclonal Anti-Blood Group ABH antibody produced in mouse

The antibody HE-10 agglutinates erythrocytes of group A but does not agglutinate erythrocytes of group B and 0. Study with specific oligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and 4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALe^b.
The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues.

Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.

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Solution in high glucose Dulbecco′s modified Eagle´s Medium (DMEM) with stable glutamine, with 15 mM sodium azide.

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