Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

HBsAg is the surface antigen of HBV (hepatitis B virus). It is secreted in the form of pleomorphic particles, mostly spherical and partly filamentous. HBV is usually spread due to percutaneous or mucosal exposure to infected blood and other body fluids.

The antibody HB5 recognizes following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Hepatitis B surface antigen (HBsAg) is a marker of infectivity.
Specificity of the antibody HB5 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB5 does not cross-block with the antibody HB3.

Purified HbsAg from human plasma.

Monoclonal Anti-HBV antigen HBsAg antibody has been used in quantitative assays.

HBsAg acts as a clinical marker and helps to specify acute or chronic infection. Presence of HBsAg indicates HBV infection. Overexpression of HBsAg is seen in infected hepatocytes.

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Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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