偶联物
PE-Cy7 conjugate
质量水平
抗体产品类型
primary antibodies
克隆
EBVCS-5, monoclonal
表单
buffered aqueous solution
种属反应性
human
技术
flow cytometry: suitable
同位素/亚型
IgG1κ
UniProt登记号
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
human ... FCER2(2208)
一般描述
CD23 (Fc epsilon RII), the low affinity IgE receptor, is a 45 kDa type II membrane glycoprotein expressed more or less on eosinophils, follicular dendritic cells, Langerhans cells, mature B cells (mainly upon activation), EBV-transformed lymphoblasts, monocytes, and subpopulation of platelets. A soluble form of 37 kDa and other its fragments were also described. CD23 mediates IgE-dependent cytotoxicity by eosinophils and macrophages, and downregulates IgE secretion in response to high levels of IgE, involving release of pro-inflammatory cytokines.
免疫原
EBV-transformed human cells
生化/生理作用
The mouse monoclonal antibody EBVCS-5 recognizes an extracellular epitope located in the stalk region of human low affinity IgE receptor (CD23) between the 37 and 25 kDa cleavage sites.
外形
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
制备说明
Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 7 (PE-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
其他说明
The antibody solution should be gently mixed before use.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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