偶联物
phycoerythrin (R-PE) conjugate
质量水平
抗体产品类型
primary antibodies
克隆
EM-35, monoclonal
表单
buffered aqueous solution
种属反应性
human
浓度
0.1 mg/ml
技术
flow cytometry: suitable
同位素/亚型
IgG1
UniProt登记号
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
human ... FOLR2(2350)
一般描述
FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta, but it can be also expressed in other tissues, including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2), including M2-like tumor-associated macrophages, which exert potent immunosuppressive functions within the tumor environment, but not GM-CSF (M1), and whose expression correlates with increased folate uptake ability.
免疫原
BW5147alpha,beta- cells
生化/生理作用
The mouse monoclonal antibody EM-35 recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid.
外形
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
制备说明
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
其他说明
The antibody solution should be gently mixed before use.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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