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Merck
CN

SAB4702151

Monoclonal Anti-CD300e, purified low endotoxin produced in mouse

别名:

CLM2, CMRF35-A5, IREM-2, LMIR6, PlgR2

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
UP-H2, monoclonal
Application:
FACS, FUNC, IP, WB
Citations:
-
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conjugate

unconjugated

antibody product type

primary antibodies

clone

UP-H2, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

1 mg/ml

technique(s)

FUNC: suitable, flow cytometry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG1κ

UniProt accession no.

storage temp.

2-8°C

Quality Level

Gene Information

human ... CD300E(342510)

General description

CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.

Immunogen

CD300e-HA-transfected cells

Biochem/physiol Actions

The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

Physical form

Phosphate buffered saline (PBS), pH 7.4

Preparation Note

Purified by protein-A affinity chromatography.
Store at 2-8°C. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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