SAB5200047
Monoclonal Anti-SHANK3 antibody produced in mouse
clone S72-16, 1 mg/mL, purified immunoglobulin
别名:
Anti-Prosap2, Anti-SHANK3, S69-46, Anti-Shank3
产品名称
Monoclonal Anti-SHANK3 antibody produced in mouse, clone S72-16, 1 mg/mL, purified immunoglobulin
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
S72-16, monoclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 190 kDa
species reactivity
mouse, rat, human
concentration
1 mg/mL
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Shank3(59312)
Biochem/physiol Actions
Detects ~190 kDa. No cross-reactivity against Shank1 or Shank2.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Immunogen
Synthetic peptide amino acids 840-857 of rat Shank3, Accession Number Q9JLU4
Physical form
Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels.
Meghan Kerrisk Campbell et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(23), 5289-5301 (2018-05-08)
Mutations or altered protein levels of SHANK3 are implicated in neurodevelopmental disorders such as Phelan-McDermid syndrome, autism spectrum disorders, and schizophrenia (Guilmatre et al., 2014). Loss of SHANK3 in mouse models results in decreased synapse density and reduction in the
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