SAB5200085
Anti-ING1 antibody produced in rabbit
250 μg/mL, affinity isolated antibody
别名:
Anti- p47ING1a, Anti-ING1, Anti-growth inhibitor ING1, Anti-p33 ING1, Anti-p33ING1b, Anti-p47
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, WB
Citations:
2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 33 kDa
species reactivity
mouse, human
concentration
250 μg/mL
technique(s)
indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Ing1(26356)
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General description
Inhibitor of growth-family member 1 (ING1) possesses plant homeodomains (PHDs). The gene ID of the protein is 26356.
Immunogen
Mouse p33 ING1 N-terminal peptide –KLH conjugates
Biochem/physiol Actions
Detects a ~33 kDa protein corresponding to the molecular mass of p33 ING1 on SDS PAGE immunoblots.
Inhibitor of growth-family member 1 (ING1) may take part in chromatin remodeling. It is a part of histone acetyltransferase complex and acts as an epigenetic modulator. Like the other members of its family, ING1 also functions as a tumor suppressor.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
TBS, 50% glycerol, 0.09% sodium azide
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Uma Karthika Rajarajacholan et al.
PLoS biology, 11(3), e1001502-e1001502 (2013-03-09)
The INhibitor of Growth (ING) proteins act as type II tumor suppressors and epigenetic regulators, being stoichiometric members of histone acetyltransferase and histone deacetylase complexes. Expression of the alternatively spliced ING1a tumor suppressor increases >10-fold during replicative senescence. ING1a overexpression
Masato Takahashi et al.
Cancer research, 62(8), 2203-2209 (2002-04-17)
The candidate tumor suppressor p33(ING1) plays an important role in inducinggrowth arrest at G(0)-G(1) phase of the cell cycle and/or promoting apoptosis in cancerous cells. p33(ING1) is reported to act as a transcriptional cofactor by associating with tumor suppressor p53
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