SAB5200112
Anti-Aquaporin-4 Antibody
rabbit polyclonal
别名:
抗 水通道蛋白 4, 抗AQP4
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
indirect immunofluorescence
western blot
western blot
Species reactivity:
rat, human, mouse
Citations:
4
Technique(s):
indirect immunofluorescence: suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗AQP4 兔抗, 1 mg/mL, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 35 kDa
species reactivity
rat, human, mouse
concentration
1 mg/mL
technique(s)
indirect immunofluorescence: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Aqp4(25293)
Features and Benefits
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Biochem/physiol Actions
检测 ~35 kDa。可检出较大的糖基化条带 ~50 kDa。
水通道蛋白 4 (AQP4) 在大鼠脑内发挥水通道的作用。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
水通道蛋白4（AQP4）在神经系统中表达。蛋白质的基因ID为25293。
Immunogen
C 末端肽
Physical form
PH 7.4 PBS、50%甘油和0.09%叠氮化钠
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Elisa Vizzaccaro et al.
Muscle & nerve, 57(5), 856-858 (2017-12-02)
Aquaporins (AQPs) are a family of transmembrane proteins involved in the maintenance of osmotic gradients. AQP4 is abundant in skeletal muscle, where it seems to be associated with glycolytic metabolism. We investigated the pattern of expression of AQP4 in normal
S Ceccariglia et al.
Neuroscience, 274, 273-288 (2014-06-10)
Trimethyltin chloride (TMT) is a neurotoxicant producing neuronal degeneration and reactive astrogliosis in the mammalian central nervous system, especially the hippocampus. A previous magnetic resonance imaging investigation in TMT-treated rats evidenced dilation of lateral ventricles, also suggesting alterations in blood-brain
Teruyuki Ishikura et al.
Journal of neuroinflammation, 18(1), 181-181 (2021-08-23)
Intractable neuropathic pain is a common symptom of neuromyelitis optica spectrum disorder (NMOSD). However, the underlying mechanism of NMOSD pain remains to be elucidated. In this study, we focused on ATP, which is one of the damage-associated molecular patterns, and
Alex J Smith et al.
Acta neuropathologica communications, 7(1), 74-74 (2019-05-10)
Redistribution of the water channel aquaporin-4 (AQP4) away from astrocyte endfeet and into parenchymal processes is a striking histological feature in mouse models of Alzheimer's disease (AD) and other neurological conditions with prominent astrogliosis. AQP4 redistribution has been proposed to
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