Monoclonal Anti-Tcp1 Alpha - Atto 390 antibody produced in rat

Tcp1 (t-complex protein ) is a chaperonin and a ATPase complex that encodes a chaperonin, localized to the cytosol.

Purified recombinant mouse TCP1 alpha construct encoding the C-terminal half of the 1.8 kb full-length Tcp 1b gene expressed in E. coli. Detects the COOH group.

Tcp1 (t-complex protein) is involved in protein folding mechanism of essential proteins such as actins, tubulin, cyclin E, α-transducin and von Hippel Lindau protein. Tcp1 participates in synthesis of proteins that make up the cytoskeleton and thus involved in cellular processes such as chromosome segregation, cell migration, and intracellular transport. Increased TCP1 gene expression is observed in cancer and upregulation elevates with the disease progression.

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PBS pH7.4, 50% glycerol, 0.1% sodium azide

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