Monoclonal Anti-FOXP3 antibody produced in mouse

Forkhead box P3 (FOXP3) is located on human chromosome Xp11.23-Xq13.3. FOXP3 is a putative DNA-binding protein and is a member of the forkhead family. The protein is mainly expressed in the CD4⁺CD25⁺ regulatory T-cell subsets.

Purified recombinant fragment of human Foxp3 expressed in E.coli.
Mouse monoclonal antibody raised against Foxp3

Monoclonal Anti-FOXP3 antibody has been used in immunohistochemistry (IHC).

Forkhead box P3 (FOXP3) plays an essential role in the development of CD4⁺CD25⁺ regulatory T cells and regulates immune homeostasis. It also acts as a transcriptional repressor. Polyadenylation signal mutation of the gene leads to immune dysregulation, polyendocrinopathy, enteropathy and X-linked inheritance (IPEX). Abnormalities in the gene expression are also associated with the pathogenesis of autism spectrum disorders (ASD) and unexplained recurrent spontaneous abortion (URSA).

Ascitic fluid containing 0.03% sodium azide.

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