SAB5500090
Anti-Cyclin D1 antibody, Rabbit monoclonal
recombinant, expressed in proprietary host, clone SP4, tissue culture supernatant
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
SP4, monoclonal
Application:
immunoblotting
immunohistochemistry
immunohistochemistry
Species reactivity:
human (tested)
Citations:
2
Technique(s):
immunoblotting: 1:25
immunohistochemistry: 1:100
immunohistochemistry: 1:100
Uniprot accession no.:
产品名称
Anti-Cyclin D1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP4, tissue culture supernatant
biological source
rabbit
recombinant
expressed in proprietary host
conjugate
unconjugated
antibody form
tissue culture supernatant
antibody product type
primary antibodies
clone
SP4, monoclonal
species reactivity
human (tested)
species reactivity (predicted by homology)
frog, dog, mouse, chicken, rat, bovine
technique(s)
immunoblotting: 1:25
immunohistochemistry: 1:100
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CCND1(595)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators, and functions in association with cdk4 and / or cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL).
Immunogen
Synthetic peptide from C-terminus of human cyclin D1.
Physical form
0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Isabel Leung et al.
Blood advances, 7(12), 2718-2730 (2022-12-06)
Therapy with CD19-directed chimeric antigen receptor (CAR) T cells has transformed the treatment of advanced B-cell malignancies. However, loss of or low antigen expression can enable tumor escape and limit the duration of responses achieved with CAR T-cell therapy. Engineering
Cindy G Avalos-de León et al.
Cells, 8(12) (2019-12-15)
In liver transplantation (LT), organ shortage has led to the use of steatotic and non-steatotic grafts from donors after cardiocirculatory death (DCD). However, these grafts, especially those with steatosis, exhibit poor post-operative outcomes. To address this problem, we investigated the
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